BRAM-COR Cleaning in Place / Sterilizing in Place systems are designed to fully meet cGMPs requirements in cleaning and sterilizing practices commonly applied in pharmaceutical process lines.
BRAM-COR CIP/SIP systems are supplied as FIXED STATIONS or as MOBILE SKIDS, with manual, semiautomatic or automatic configuration.
CIP systems can be equipped with different utilities for heating, such as:
Sterilization by heat is one of the most widely used systems in pharmaceutical processes. BRAM-COR process tanks are equipped with a thermoregulation system, making it possible to heat the internal temperature of the tank, and therefore the content, up to the sterilization temperature (> 121°C), a state in which most of the microorganisms and enzymes are inactivated, guaranteeing the sterility of the final product.
BRAM-COR process technology foresees the achievement of the final goal through the following instrumentation/controls.
For Thermolabile products, BRAM-COR offers methods of product sterilization through filtration, which does not destroy microorganisms but removes them through adsorption and trapping mechanisms that occur by passing the product through hydrophilic membrane cartridges.
BRAM-COR dual and single filtration skids offer several options and advantages:
The filtration skids come with a wide range of instruments available upon request: